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portada Xenobiotic Metabolic Enzymes: Bioactivation and Antioxidant Defense: Bioactivation and Antioxidant Defense:
Type
Physical Book
Publisher
Author
Year
2020
Language
English
Pages
239
Format
Hardcover
ISBN13
9783030416782
Edition No.
1
Categories

Xenobiotic Metabolic Enzymes: Bioactivation and Antioxidant Defense: Bioactivation and Antioxidant Defense:

Chang-Hwei Chen (Author) · Springer · Hardcover

Xenobiotic Metabolic Enzymes: Bioactivation and Antioxidant Defense: Bioactivation and Antioxidant Defense: - Chang-Hwei Chen

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Synopsis "Xenobiotic Metabolic Enzymes: Bioactivation and Antioxidant Defense: Bioactivation and Antioxidant Defense: "

This book provides a comprehensive, organized, and concise overview of xenobiotic metabolic enzymes and their health implications. The subjects addressed are broad in scope with an emphasis on recent advances in research on biochemical and biomedical aspects of these enzymes. The xenobiotics discussed include not just drugs, but also food, smoke, and other environmental chemicals. The subjects covered in this work include: metabolic enzymes and their catalyzed reactions, reactive intermediates generated from metabolic activation, oxidative stress mediated by electrophilic reactive intermediates, bioactivation - mediated cellular and functional damages, activation of Nrf2 – ARE pathway, genetic variations affecting metabolic enzyme expression, enzyme polymorphisms affecting xenobiotic - mediated toxicity, induction of metabolic enzymes for health benefits, and a diversity of metabolic enzyme modulators.

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