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portada tyrosine phosphorylation/dephosphorylation and downstream signalling
Type
Physical Book
Publisher
Year
2011
Language
English
Pages
376
Format
Paperback
Dimensions
23.4 x 15.6 x 2.1 cm
Weight
0.55 kg.
ISBN
3642782493
ISBN13
9783642782497

tyrosine phosphorylation/dephosphorylation and downstream signalling

Ludwig M. G. Jr. Heilmeyer (Illustrated by) · Springer · Paperback

tyrosine phosphorylation/dephosphorylation and downstream signalling - Heilmeyer, Ludwig M. G. Jr.

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Synopsis "tyrosine phosphorylation/dephosphorylation and downstream signalling"

Nearly every cellular activity, such as cell growth, proliferation, protein synthesis, and nuclear division, is regulated by protein phosphorylation/dephosphorylation on tyrosine residues as initiation events.Synchronization occurs through interaction of protein tyrosine kinases and phosphatases. This book unveils signal pathways that connect extracellular signals with changes of phosphorylation state of target proteins allowing coordinated and integrated modulation of mitogenic signalling. Specifically, cascades involving protein serine/threonine kinases and connections to phosphoinositides derived second messengers are discussed.

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