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portada Tumor Profiling: Methods and Protocols
Type
Physical Book
Publisher
Author
Language
English
Pages
268
Format
Hardcover
Dimensions
26.2 x 25.1 x 1.8 cm
Weight
0.73 kg.
ISBN13
9781493990023
Categories

Tumor Profiling: Methods and Protocols

Murray, Sarah S. (Author) · Humana · Hardcover

Tumor Profiling: Methods and Protocols - Murray, Sarah S.

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Synopsis "Tumor Profiling: Methods and Protocols"

This book provides a practical guide to current methods for profiling and interpreting genomic alterations in tumors. Chapters detail methods to interrogate DNA variation, RNA expression, and epigenetic changes using both next-generation sequencing and microarray techniques, common bioinformatics and annotation tools to glean relevant driver genomic events, and different performance characteristics as well as quality metrics necessary for the robust validation of tumor profiling as a diagnostic test for medical laboratories. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Tumor Profiling: Methods and Protocols aims to be a useful resource for learning about technical details, applications, and strengths and limitations of the latest technologies as applied to this increasingly important field.

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