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portada The Intervertebral Disc: Molecular and Structural Studies of the Disc in Health and Disease
Type
Physical Book
Publisher
Author
Language
English
Pages
446
Format
Paperback
ISBN13
9783709119433
Edition No.
1

The Intervertebral Disc: Molecular and Structural Studies of the Disc in Health and Disease

Shapiro Irving M.,Risbud Makarand V. (Author) · Springer · Paperback

The Intervertebral Disc: Molecular and Structural Studies of the Disc in Health and Disease - Shapiro Irving M.,Risbud Makarand V.

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Synopsis "The Intervertebral Disc: Molecular and Structural Studies of the Disc in Health and Disease"

The intervertebral disc is a complex structure that separates opposing vertebrae, permits a wide range of motion, and accommodates high biomechanical forces. Disc degeneration leads to a loss of function and is often associated with excruciating pain. Written by leading scientists and clinicians, the first part of the book provides a review of the basic biology of the disc in health and disease. The second part considers strategies to mitigate the effects of disc degeneration and discusses the possibility of engineering replacement tissues. The final section is devoted to approaches to model normal development and elucidate the pathogenesis of degenerative disc disease using animal, organ and cell culture techniques. The book bridges the gap between the basic and clinical sciences; the target audience includes basic scientists, orthopaedists and neurologists, while at the same time appealing to the needs of graduate students, medical students, interns and fellows.

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