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portada Primary Aldosteronism: Molecular Genetics, Endocrinology, and Translational Medicine
Type
Physical Book
Publisher
Author
Language
English
Pages
233
Format
Paperback
Dimensions
23.4x15.6x1.3 cm
Weight
0.35 kg.
ISBN13
9781493946228
Categories

Primary Aldosteronism: Molecular Genetics, Endocrinology, and Translational Medicine

Hellman, Per (Author) · Springer · Paperback

Primary Aldosteronism: Molecular Genetics, Endocrinology, and Translational Medicine - Hellman, Per

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Synopsis "Primary Aldosteronism: Molecular Genetics, Endocrinology, and Translational Medicine"

Primary Aldosteronism (PA) is a disease caused by the overproduction of aldosterone hormone from the adrenal glands. PA causes hypertension and the majority with this disease are undiagnosed for PA. There are new insights into this matter by using biochemistry as well as advanced radiology. In 2011, a breakthrough in the genetic derangements came, identifying a mutated potassium channel gene - KCNJ5 - in about 40% of PA with adenoma. Chapters in this book include a history of the disorder, epidemiology, genetics derangements, the KCNJ5 mutations and phenotype and more.

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