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portada platinum-based drugs in cancer therapy
Type
Physical Book
Illustrated by
Publisher
Author
Year
2010
Language
English
Pages
341
Format
Paperback
Dimensions
23.4 x 15.6 x 1.9 cm
Weight
0.50 kg.
ISBN
1617370916
ISBN13
9781617370915
Categories

platinum-based drugs in cancer therapy

Lloyd R. Kelland (Illustrated by) · Nicholas P. Farrell (Illustrated by) · Humana · Paperback

platinum-based drugs in cancer therapy - Kelland, Lloyd R. ; Farrell, Nicholas P.

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Synopsis "platinum-based drugs in cancer therapy"

Leading international experts comprehensively review all aspects of platinum anticancer drugs and their current use in treatment, as well as examining their future therapeutic prospects. Writing from a variety of disciplines, these authorities discuss the chemistry of cisplatin in aqueous solution, the molecular interaction of platinum drugs with DNA, and such exciting new areas as DNA mismatch repair and replicative bypass, apoptosis, and the transport of platinum drugs into tumor cells. The emergent platinum drugs of the future-orally active agents, the sterically hindered ZD0473, and the polynuclear charged platinum BBR3464-are also fully considered. Timely and interdisciplinary, Platinum-Based Drugs in Cancer Therapy offers cancer therapeutics specialists an illuminating survey of every aspect of platinum drugs from mechanisms of action to toxicology, tumor resistance, and new analogs.

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