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portada multiple origins of sex differences in brain: neuroendocrine functions and their pathologies
Type
Physical Book
Illustrated by
Publisher
Author
Year
2013
Language
English
Pages
181
Format
Hardcover
Dimensions
24.2 x 16.1 x 1.5 cm
Weight
0.42 kg.
ISBN
3642337201
ISBN13
9783642337208
Categories

multiple origins of sex differences in brain: neuroendocrine functions and their pathologies

Donald W. Pfaff (Illustrated by) · Yves Christen (Illustrated by) · Springer · Hardcover

multiple origins of sex differences in brain: neuroendocrine functions and their pathologies - Pfaff, Donald W. ; Christen, Yves

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Synopsis "multiple origins of sex differences in brain: neuroendocrine functions and their pathologies"

In theoretical terms, sex differences in brains and behaviors of laboratory animals offer the possibility of fascinating scientific studies on a range of molecular phenomena such as genomic imprinting, DNA methylation, chromatin protein modification, non-coding DNA, potentially resulting in important neuroanatomical and neurochemical sex differences in the brain. Such sex differences could arise consequent to exposures to testosterone early in development, or to other effects deriving from the Y chromosome. However, this general subject has been treated with much hyperbole. Historically, sex differences were assumed to be present where they did not really exist, e.g. with respect to mathematics, executive leadership, etc. etc. Under what circumstances do we really care about sex differences in brain and behavior? These circumstances concern human maladies whose diagnoses are much different between boys and girls, or between women and men. Prominent examples discussed in this volume include autism, attention deficit hyperactivity disorders and congenital adrenal hyperplasia. In fact, infant boys are more susceptible than infant girls to a variety of disorders that arise early in development. This volume then ends with a consideration of effects of estrogenic hormones on the injured brain, and their roles as protective agents.

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