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portada Environmental Neuroscience. Advancing the Understanding of How Chemical Exposures Impact Brain Health and Disease: Proceedings of a Workshop
Type
Physical Book
Publisher
Author
Year
2021
Pages
86
Format
Paperback
Dimensions
22.90 x 15.20 x 2.50 cm
ISBN13
9780309683098

Environmental Neuroscience. Advancing the Understanding of How Chemical Exposures Impact Brain Health and Disease: Proceedings of a Workshop

Board On Environmental Studies And Toxicology;Sheena M. Posey Norris;Lisa Bain;Clare Stroud;Health And Medicine Division;Forum On Neuroscience And Nervous System Disorders;Engineering, And Medicine National Academies Of Sciences;Division On Earth And Life (Author) · National Academies Press · Paperback

Environmental Neuroscience. Advancing the Understanding of How Chemical Exposures Impact Brain Health and Disease: Proceedings of a Workshop - Board on Environmental Studies and Toxicology;Sheena M. Posey Norris;Lisa Bain;Clare Stroud;Health and Medicine Division;Forum on Neuroscience and Nervous System Disorders;Engineering, and Medicine National Academies of Sciences;Division on Earth and Life

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Synopsis "Environmental Neuroscience. Advancing the Understanding of How Chemical Exposures Impact Brain Health and Disease: Proceedings of a Workshop"

Humans are potentially exposed to more than 80,000 toxic chemicals in the environment, yet their impacts on brain health and disease are not well understood. The sheer number of these chemicals has overwhelmed the ability to determine their individual toxicity, much less potential interactive effects. Early life exposures to chemicals can have permanent consequences for neurodevelopment and for neurodegeneration in later life. Toxic effects resulting from chemical exposure can interact with other risk factors such as prenatal stress, and persistence of some chemicals in the brain over time may result in cumulative toxicity. Because neurodevelopmental and neurodegenerative disorders - such as attention-deficit hyperactivity disorder and Parkinson's disease - cannot be fully explained by genetic risk factors alone, understanding the role of individual environmental chemical exposures is critical. On June 25, 2020, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders hosted a workshop to lay the foundation for future advances in environmental neuroscience. The workshop was designed to explore new opportunities to bridge the gap between what is known about the genetic contribution to brain disorders and what is known, and not known, about the contribution of environmental influences, as well as to discuss what is known about how genetic and environmental factors interact. This publication summarizes the presentation and discussion of the workshop. Table of ContentsFront Matter1 Introduction and Background2 Neurotoxicants and Their Risks to Human Health3 The Exposome and Exploring the Multiple Factors That Contribute to Neurotoxicity4 Chemical Toxicants as Drivers of Abnormal Neurodevelopment and Neurodegeneration5 Research Gaps and Opportunities6 Potential Opportunities for Action and Multidisciplinary CollaborationsAppendix A: ReferencesAppendix B: Workshop Agenda

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