Name: Attenuation of Th1 Cell Immune Response: ¿Through Galectin-9-TIM-3 Interactions Inhibits Autoimmune Diabetes in NOD Mice
SKU: 69036325
Price: 192.67 NZD
Availability: InStock
Author: Chou, Feng-Cheng
ISBN: 9783639826081

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portada Attenuation of Th1 Cell Immune Response: ¿Through Galectin-9-TIM-3 Interactions Inhibits Autoimmune Diabetes in NOD Mice

Attenuation of Th1 Cell Immune Response: ¿Through Galectin-9-TIM-3 Interactions Inhibits Autoimmune Diabetes in NOD Mice

Type

Physical Book

Publisher

VDM Verlag

Author

Chou, Feng-Cheng

Language

English

Pages

ISBN13

9783639826081

Attenuation of Th1 Cell Immune Response: ¿Through Galectin-9-TIM-3 Interactions Inhibits Autoimmune Diabetes in NOD Mice

Chou, Feng-Cheng (Author) · VDM Verlag · Physical Book

New Book Imported to New Zealand

Delivery: 30 Nov - 07 Dec

NZ$ 192.67

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NZ$ 192.67

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Synopsis "Attenuation of Th1 Cell Immune Response: ¿Through Galectin-9-TIM-3 Interactions Inhibits Autoimmune Diabetes in NOD Mice"

Galectin-9, widely expressed in many tissues, regulates Th1 cells and induces their apoptosis through its receptor, T-cell immunoglobulin mucin 3 (TIM-3), which is mainly expressed on terminally differentiated Th1 cells. Type 1 diabetes is a Th1-dominant autoimmune disease that specifically destroys insulin-producing cells. To suppress the Th1 immune response in the development of autoimmune diabetes, we overexpressed galectin-9 in NOD mice by injection of a plasmid encoding galectin-9.