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portada deciphering growth
Type
Physical Book
Illustrated by
Publisher
Author
Year
2005
Language
English
Pages
155
Format
Hardcover
Dimensions
23.4 x 15.6 x 1.1 cm
Weight
0.42 kg.
ISBN
3540261923
ISBN13
9783540261926
Categories

deciphering growth

J. -C Carel (Illustrated by) · Paul A. Kelly (Illustrated by) · Springer · Hardcover

deciphering growth - Carel, J. -C ; Kelly, Paul A.

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Synopsis "deciphering growth"

In mammals, the major factors involved in the regulation of body growth are known: insulin-like growth factors (IGF) are key regulators of somatic growth. Growth hormone (GH), secreted by the pituitary gland, directly regulates circulating levels of IGF-I, which is the major coordinator of spatio-temporal growth of the organism. In humans, growth is even more complex, involving a number of specific characteristics not found in other species. These include rapid intrauterine growth, deceleration just after birth, a mid-childhood growth spurt, a second deceleration before puberty, an adolescent growth spurt, and finally full statural growth, which is seen somewhat later. The combined knowledge concerning the endocrine and paracrine aspects of growth have led to the introduction of treatment regimens, most effective in GH-deficient children. However, size depends on the combination of a number of genetic factors, and there remain several aspects of this complex process still poorly understood.

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